Bridging spinal cord injuries with polylactic acid electrospun fibers
نویسندگان
چکیده
منابع مشابه
Bridging spinal cord injuries
One strategy for spinal cord injury repair is to make cellular bridges that support axon regeneration. However, the bridging cells often fail to integrate with host tissue and may lead to increased pain sensitivity. Recent work has tested bridging with two forms of progenitor-derived astrocyte. One type integrates, suppresses scar formation and promotes axon regeneration, whereas another very s...
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Cinnamaldehyde (CA) was successfully encapsulated in β-cyclodextrin (β-CD), and polylactic acid (PLA)-based composite fibers were prepared by incorporating CA/β-CD via electrospinning. Morphological, structural, spectral, and antibacterial properties of different weight ratios of PLA:β-CD/CA (88:12, 94:6, 97:3, and 98.5:1.5) and PLA/CA/β-CD fibers were investigated. PLA and CA/β-CD were incorpo...
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A recent article by Dr Robert Heimburger in the Journal was titled, “Is there hope for return of function in lower extremities paralyzed by spinal cord injury?” This question can be answered by showing that innovative attempts are currently being pursued in the hope, as requested by Dr Heimburger, to improve the neurologic results of patients who tragically sustain a spinal cord injury (SCI). D...
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Biotin has been successfully incorporated into polylactic acid (PLA) nanofibers through electrospinning to prepare membrane substrates for biosensors based on biotin–streptavidin specific binding. Biotin incorporated PLA nanofiber membranes were characterized with scanning electron microscopy (SEM), electron probe microanalysis (EPMA), and confocal microscopy. Under optimized conditions, small ...
متن کاملHealing Spinal Cord Injuries
Unlike those in the periphery, nerve fibers in the central nervous system (brain and spinal cord) do not recover from traumatic injury. This makes disabilities from spinal cord damage permanent, with the severity depending on the location of the cord injury. Neck injuries can paralyze the torso and limbs, while lower back injuries can impair movement below the waist. The spinal cord is a bundle...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.02944